Ammonium → (2-(Benzyloxy)-3-tert-butylphenyl)(2-methoxybiphenyl-3-yl)(phenyl)methanol

HRID 178745Notes

Reaction equation

HRID 178745 reaction equation
[Br:1][c:2]1[c:3]([O:14][CH3:15])[c:4](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1.[CH2:16]([Li:17])[CH2:18][CH2:19][CH3:20].[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[O:28][c:29]1[c:30]([C:39](=[O:40])[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:31][cH:32][cH:33][c:34]1[C:35]([CH3:36])([CH3:37])[CH3:38].[Cl-:47].[NH4+:48].[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1>>[c:2]1([C:39]([c:30]2[c:29]([O:28][CH2:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[c:34]([C:35]([CH3:36])([CH3:37])[CH3:38])[cH:33][cH:32][cH:31]2)([OH:40])[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:3]([O:14][CH3:15])[c:4](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 183474973-Bromo-2-methoxy-1,1'-biphenylHCID 58238504(2-(Benzyloxy)-3-tert-butylphenyl)(phenyl)methanoneHCID 178418339Butyllithium

Product 1

HCID 58238509(2-(Benzyloxy)-3-tert-butylphenyl)(2-methoxybiphenyl-3-yl)(phenyl)methanol

Sources & evidence

ORD record
ord-85f200cc4e304e409407a8302ebfed8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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