反应详情

To 3-(N-tert-butoxycarbonylamino)-N-(4-chlorophenyl)-pyridine-4-carboxamide (552 mg, 1.59 mmol) was added trifluoroacetic acid (3 mL, 38.95 mmol). After stirring for 10 min, the reaction mixture was concentrated, diluted with CH2Cl2, washed with satd Na2CO3, dried (Na2SO4) and concentrated to give the title compound (367 mg, 93%) as a pale yellow solid.

1. concentrationthe reaction mixture was concentrated
2. additiondiluted with CH2Cl2
3. washwashed with satd Na2CO3
4. dry with materialdried (Na2SO4)
5. concentrationconcentrated