Methanol → HCID 21900164, compound

HRID 1788258Notes

Reaction equation

[OH-].[CH2:2]([N+:6]([CH2:15][CH2:16][CH2:17][CH3:18])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:7][CH2:8][CH2:9][CH3:10])[CH2:3][CH2:4][CH3:5].CO.[C:21]([OH:26])(=[O:25])[CH:22]([CH3:24])[CH3:23]>>[C:21]([O-:26])(=[O:25])[CH:22]([CH3:24])[CH3:23].[CH2:15]([N+:6]([CH2:2][CH2:3][CH2:4][CH3:5])([CH2:7][CH2:8][CH2:9][CH3:10])[CH2:11][CH2:12][CH2:13][CH3:14])[CH2:16][CH2:17][CH3:18]

Participants

Reactant 3

HCID 887Methanol

HCID 6590Isobutyric Acid

HCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 21900164HCID 21900164, compound

Procedure

Alternatively, a 1M solution of tetrabutylammonium hydroxide in methanol (1 L, 1 mol) and isobutyric acid (88.5 g, 1 mol) was stirred at ambient temperature for 30 min. The solvent was removed in vacuo to afford the title compound (5) as a waxy solid, which was used without further purification.

Workup

customThe solvent was removed in vacuo

Sources & evidence

ORD record: ord-55b291c8e2044046a869b5ae58a39430
Source dataset: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07511158B2

Reaction notes

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