Ethylene carbonate → HCID 22036371, compound

HRID 1789716Notes

Reaction equation

HRID 1789716 reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1.C1(=O)O[CH2:15][CH2:14][O:13]1>CN(C=O)C>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[O:9][CH2:15][CH2:14][OH:13]

Participants

4

Reactant 2

HCID 7303Ethylene carbonateHCID 73763-(Trifluoromethyl)phenol

Product 1

HCID 22036371HCID 22036371, compoundYield 64%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared according to the procedure of Example 114, Step 1 starting from 3-trifluoromethylphenol (3.89 g, 24 mmol) and ethylene carbonate (1.76 g, 20 mmol) with the exception that no DMF was used. Oil; yield 64%. MS m/z 206 (M)+.

Sources & evidence

ORD record
ord-736f4940698043c6bc8cd5e9d9295cd0
Source dataset
uspto-grants-2006_07
Patent number
US07071180B2

Reaction notes

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