反应详情

Conc. hydrochloric acid (2 mL) was added to 2-acetylsulfanylmethyl-3-(6-tert-butoxycarbonylamino-2-methyl-pyridin-3-yl)-propionic acid ethyl ester (77 mg, 0.19 mmol) under argon. The reaction was heated to reflux for 110 min and was then concentrated under reduced pressure to give the title compound (39 mg, 76%) as the hydrochloride salt.

1. temperatureThe reaction was heated
2. temperatureto reflux for 110 min
3. concentrationwas then concentrated under reduced pressure