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HRID1790472

反应详情

EQUATION

反应方程式

HRID 1790472 的结构方程式

REACTANTS

反应物

3
结构：O=C1CNC(=O)N1
HCID10006

2,4-Imidazolidinedione

C3H4N2O2

结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：Fc1ccc(CCN2CCC(N3CCc4ccc(CCl)cc43)CC2)cc1
HCID22038253

未命名化合物

PRODUCTS

生成物

1
结构：O=C1CNC(=O)N1Cc1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2
HCID22038074

未命名化合物

收率 49.1%

PROCEDURE

实验过程

Hydantoin (130 mg), 60% sodium hydride (54 mg) and 1-[1-(4-fluorophenethyl)piperidin-4-yl]-6-chloromethylindoline (400 mg) were treated as in Example 202 to give the title compound (230 mg) as a white powder (yield: 49%).