反应详情

18.7 g of 4 is dissolved in 500 ml of benzene, 30 ml of ethylene glycol and 1 g of p-toluenesulfonic acid are added and heated under nitrogen in a water separator for 12 hours. After cooling, sodium bicarbonate solution is added, extracted with ethyl acetate, dried on sodium sulfate and concentrated by evaporation, whereby 23 g of title compound 5 accumulates as a colorless oil.

1. temperatureAfter cooling
2. extractionextracted with ethyl acetate
3. customdried on sodium sulfate
4. concentrationconcentrated by evaporation, whereby 23 g of title compound 5 accumulates as a colorless oil