Hydrochloric Acid → 7-Methoxy-4-((6-(1,2,3,6-tetrahydropyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methoxy)quinoline

HRID 179093Notes

Reaction equation

HRID 179093 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([O:13][CH2:14][c:15]3[n:16][n:17][c:18]4[n:19]3[cH:20][c:21]([C:24]3=[CH:25][CH2:26][N:27]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:28][CH2:29]3)[cH:22][cH:23]4)[cH:8][cH:9][n:10][c:11]2[cH:12]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH3:45][OH:46].[ClH:37]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([O:13][CH2:14][c:15]3[n:16][n:17][c:18]4[n:19]3[cH:20][c:21]([C:24]3=[CH:25][CH2:26][NH:27][CH2:28][CH2:29]3)[cH:22][cH:23]4)[cH:8][cH:9][n:10][c:11]2[cH:12]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8471TriethylamineHCID 57691269tert-Butyl 4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 576911057-Methoxy-4-((6-(1,2,3,6-tetrahydropyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methoxy)quinoline

Sources & evidence

ORD record
ord-9395627df7ec4fdb9ded78e19effe7c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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