Indoline → 4-Chloro-1-(2,3-dihydro-1H-indol-1-yl)butan-1-one

HRID 1791162Notes

Reaction equation

[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[Cl:10][CH2:11][CH2:12][CH2:13][C:14](Cl)=[O:15]>>[Cl:10][CH2:11][CH2:12][CH2:13][C:14]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1)=[O:15]

Participants

Reactant 2

HCID 10328Indoline

HCID 783704-Chlorobutyryl chloride

Product 1

HCID 35980624-Chloro-1-(2,3-dihydro-1H-indol-1-yl)butan-1-one

Procedure

from 2,3-dihydro-1H-indole and 4-chlorobutanoyl chloride

Sources & evidence

ORD record: ord-d3a524826c144ae7a4391a161a3c47f7
Source dataset: uspto-grants-2006_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07074796B2

Reaction notes

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