Water → Tert-butyl 4-(1-(4-chlorophenyl)-2-sulfamoylethylcarbamoyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-ylcarbamate

HRID 179222Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 179222
[C:25]([CH3:26])([CH3:27])([CH3:28])[O:29][C:30](=[O:31])[NH:32][C:33]1([C:48](=[O:49])[OH:50])[CH2:34][CH2:35][N:36]([c:39]2[c:40]3[c:41]([n:42][cH:43][n:44]2)[nH:45][cH:46][cH:47]3)[CH2:37][CH2:38]1.[CH2:51]([N:52]([CH:53]([CH3:54])[CH3:55])[CH:56]([CH3:57])[CH3:58])[CH3:59].[CH3:74][N:75]1[CH2:76][CH2:77][CH2:78][C:79]1=[O:80].[NH2:60][CH:61]([CH2:62][S:63](=[O:64])(=[O:65])[NH2:66])[c:67]1[cH:68][cH:69][c:70]([Cl:73])[cH:71][cH:72]1.[OH2:81].[P-:1]([F:2])([F:3])([F:4])([F:5])([F:6])[F:7].[n:8]1([O:9][C:10]([N:11]([CH3:12])[CH3:13])=[N+:14]([CH3:15])[CH3:16])[c:17]2[n:18][cH:19][cH:20][cH:21][c:22]2[n:23][n:24]1>>[C:25]([CH3:26])([CH3:27])([CH3:28])[O:29][C:30](=[O:31])[NH:32][C:33]1([C:48](=[O:50])[NH:60][CH:61]([CH2:62][S:63](=[O:64])(=[O:65])[NH2:66])[c:67]2[cH:68][cH:69][c:70]([Cl:73])[cH:71][cH:72]2)[CH2:34][CH2:35][N:36]([c:39]2[c:40]3[c:41]([n:42][cH:43][n:44]2)[nH:45][cH:46][cH:47]3)[CH2:37][CH2:38]1

Komponenten

8

Edukt 7

HCID 962WaterHCID 9886HexafluorophosphateHCID 13387N-methyl-2-pyrrolidoneHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 577503602-Amino-2-(4-chlorophenyl)ethanesulfonamideHCID 577503944-((tert-Butoxycarbonyl)amino)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid

Produkt 1

HCID 57750289Tert-butyl 4-(1-(4-chlorophenyl)-2-sulfamoylethylcarbamoyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-ylcarbamate

Quellen und Nachweise

ORD-Eintrag
ord-b4c7690466fe4678b5f842c2d06bcb6c
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Notizen zur Reaktion

Wird geladen…