Hydrochloric Acid → HCID 178488642, compound

HRID 1792632Notes

Reaction equation

HRID 1792632 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:19]4[C:20]([CH3:43])=[N:21][N:22](C(C5C=CC=CC=5)(C5C=CC=CC=5)C5C=CC=CC=5)[CH:23]=4)[CH:17]=3)[N:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[ClH:44]>C(OCC)(=O)C>[ClH:44].[ClH:44].[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]([C:19]4[C:20]([CH3:43])=[N:21][NH:22][CH:23]=4)[CH:17]=3)[N:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 23537500HCID 23537500, compound

Product 1

HCID 178488642HCID 178488642, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A free product obtained by the same procedure as in Example 1065 from 210 mg 4-(6-methoxypyridin-3-yl)-6-(3-methyl-1-trityl-1H-pyrazol-4-yl) quinoline obtained in Example 1064 was treated with 4 N hydrogen chloride solution in ethyl acetate to give 16 mg of the title compound as a pale yellow solid.

Sources & evidence

ORD record
ord-6f1dca8906b24deeb23e366321cf4db2
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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