Oxalyl chloride → 2,4-Dichlorobenzoyl isocyanate

HRID 1792743Notes

Reaction equation

HRID 1792743 reaction equation
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:13](Cl)=[O:14]>ClCCl>[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[CH:7][C:3]=1[C:4]([N:6]=[C:13]=[O:14])=[O:5]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 755562,4-Dichlorobenzamide

Product 1

HCID 116298872,4-Dichlorobenzoyl isocyanate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2,4-Dichlorobenzamide was dissolved in dichloromethane, after which 1.5 eq. of oxalyl chloride were added and the mixture was heated to reflux for 16 hours. The reaction mixture was then concentrated under high vacuum and reacted in step b without any further purification.

Workup

  1. temperaturethe mixture was heated
  2. temperatureto reflux for 16 hours
  3. concentrationThe reaction mixture was then concentrated under high vacuum
  4. customreacted in step b without any further purification

Sources & evidence

ORD record
ord-da622c2e851144e18b5e32b81f602c38
Source dataset
uspto-grants-2006_07
Patent number
US07078404B2

Reaction notes

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