HRID1795130

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24758

Sodium hydride

HNa

HCID6424661

5-(Bromomethyl)-2-chloropyridine

C6H5BrClN

HCID22185753

未命名化合物

PRODUCTS

生成物

HCID22185759

[(6-Chloropyridin-3-yl)methyl](3,4,4-trifluorobut-3-en-1-yl)propanedinitrile

C13H9ClF3N3

收率 60.9%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

By using (3,4,4-trifluoro-3-butenyl)malononitrile (0.21 g), N,N-dimethylformamide (5 ml), sodium hydride (60% in oil, 0.05 g) and 3-bromomethyl-6-chloropyridine (0.28 g) according to the similar method described in Production Example 1 was obtained 0.22 g of 2-((6-Chloro-3-pyridyl)methyl)-2-(3,4,4-trifluoro-3-butenyl)malononitrile represented by the following formula (the present invention compound (3)).