Methylamine → HCID 22217724, compound

HRID 1795372Notes

Reaction equation

HRID 1795372 reaction equation
[C:1]([NH:4][C:5]1[CH:14]=[CH:13][CH:12]=[C:11]2[C:6]=1[CH:7]=[CH:8][CH:9]=[C:10]2[S:15](Cl)(=[O:17])=[O:16])(=[O:3])[CH3:2].[CH3:19][NH2:20]>C(O)C>[CH3:19][NH:20][S:15]([C:10]1[CH:9]=[CH:8][CH:7]=[C:6]2[C:11]=1[CH:12]=[CH:13][CH:14]=[C:5]2[NH:4][C:1](=[O:3])[CH3:2])(=[O:17])=[O:16]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 50103065-Acetamidonaphthalene-1-sulfonyl chloride

Product 1

HCID 22217724HCID 22217724, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

1.10 g of 5-acetylaminonaphthalene-1-sulfonyl chloride is dissolved in 8 mL of ethanol and 8 mL of methylamine solution in ethanol are added dropwise. Then the resulting mixture is stirred at reflux temperature for 3.5 hours and the solvent is distilled off in vacuo. The residue is purified by chromatography. Yield: 0.50 g.

Workup

  1. temperatureat reflux temperature for 3.5 hours
  2. distillationthe solvent is distilled off in vacuo
  3. customThe residue is purified by chromatography

Sources & evidence

ORD record
ord-c1313fc8d512488a9ada1cbece861b4f
Source dataset
uspto-grants-2006_04
Patent number
US07026475B2

Reaction notes

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