反应详情

Following the general procedure 2C, crude 4-[(cyclopropylmethyl)-amino]-3-nitrobenzonitrile (920 mg, 4.24 mmol) was hydrogenated for 2 h (35 psi) in 40 mL of EtOAc to yield 750 mg crude product (95%) and was used for the next step without further purification. MS (ESI) (M+H)+=188.