Phenylhydrazine → HCID 178515195, compound

HRID 1797907Notes

Reaction equation

HRID 1797907 reaction equation
[C:1]1([N:7]2[C:19](=[O:20])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=4[C:9]3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.ClC1C2C(=CC=C([C:32]([F:35])([F:34])[F:33])C=2)N=CC=1C(OCC)=O.C1(NN)C=CC=CC=1>>[C:1]1([N:7]2[C:19](=[O:20])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[CH:15][C:16]([C:32]([F:35])([F:34])[F:33])=[CH:17][C:18]=4[C:9]3=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 7516PhenylhydrazineHCID 4322147Ethyl 4-chloro-6-(trifluoromethyl)quinoline-3-carboxylateHCID 178515184HCID 178515184, compound

Product 1

HCID 178515195HCID 178515195, compound

Procedure

The title compound was prepared following the procedure described in Step 3 of the synthesis of 4a, using 3h and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm):7.21 (1H, m), 7.42 (2H, t, J=7.56 Hz), 7.97 (1H, d, J=2.20 Hz), 8.00 (1H, d, J=2.20 Hz), 8.20 (1H, ddd, J=7.41, 1.10, 0.83 Hz), 8.43 (2H, dd, J=1.33, 0.83 Hz), 8.82 (1H, s). m/z 330.2 (MH+).

Sources & evidence

ORD record
ord-d664329faa5b4f7fa5abf36ff50b4b62
Source dataset
uspto-grants-2013_01
Patent number
US08343957B2

Reaction notes

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