反应详情

1-(cyclopropylthio)-4-methoxybenzene (300 mg, 1.66 mmol) was dissolved in 8 mL MeOH and Water (1:1). Oxone (4.9 g, 6.66 mmol) was added and the mixture was stirred overnight. 1N HCl was used to dissolve the salts and ethyl acetate was added to extract the product. The organic extract was washed with 1N HCl (3×) and brine, dried over sodium sulfate, and the solvent was removed under reduced pressure to obtain the crude product which is used without further purification.

1. additionwas added
2. extractionto extract the product
3. extractionThe organic extract
4. washwas washed with 1N HCl (3×) and brine
5. dry with materialdried over sodium sulfate
6. customthe solvent was removed under reduced pressure