Methylparaben → Benzoic acid, 4-[(2E)-2-buten-1-yloxy]-

HRID 1799256Notes

Reaction equation

HRID 1799256 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8]C)=[O:7])=[CH:4][CH:3]=1.[CH2:12](O)/[CH:13]=[CH:14]/[CH3:15]>>[CH2:12]([O:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)/[CH:13]=[CH:14]/[CH3:15]

Participants

3

Reactant 2

HCID 7456MethylparabenHCID 637922trans-Crotyl alcohol

Product 1

HCID 23321309Benzoic acid, 4-[(2E)-2-buten-1-yloxy]-Yield 91.4%

Procedure

A reaction similar to that described in Example 1 (1a) was conducted using methyl 4-hydroxybenzoate (5.00 g, 32.9 mmol) and trans-crotyl alcohol (manufactured by Fluka, 2.37 g, 32.9 mmol) to give 5.78 g of the title compound (white powder, yield: 91%).

Workup

  1. customA reaction similar to

Sources & evidence

ORD record
ord-414aabce67944881819f211b8a8ecff2
Source dataset
uspto-grants-2013_01
Patent number
US08344029B2

Reaction notes

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