反应详情

The title material was prepared as described for the synthesis of (1-methyl-4-phenylpiperidin-4-yl)methanamine (Example B above) in using 2-(tert-butyldimethylsilyloxy)acetaldehyde and by doing an acidic work-up (HCl 5N) after the reductive amination to remove the protecting group. LC/MS (M+H)+: 235. HPLC ret. time (Condition A): 0.143 min.

1. customto remove the protecting group
2. custom0.143 min.