HCID 67972218, compound → HCID 67060710, compound

HRID 1804604Notes

Reaction equation

HRID 1804604 reaction equation
[CH:1]1([N:4]2[C:8]([CH:9]3[CH2:14][CH2:13][N:12](C(OC(C)(C)C)=O)[CH2:11][CH2:10]3)=[N:7][N:6]=[N:5]2)[CH2:3][CH2:2]1>Cl.O1CCOCC1>[CH:1]1([N:4]2[C:8]([CH:9]3[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]3)=[N:7][N:6]=[N:5]2)[CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 67972218HCID 67972218, compound

Product 1

HCID 67060710HCID 67060710, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 312751,4-DioxaneSolvent

Procedure

The title compound from Step B above (200 mg, 0.68 mmol) was dissolved in 4 M HCl in dioxane (4.0 mL) and stirred at RT for 1 h. The product was concentrated under reduced pressure and dried under high vacuum to the title compound (i-37) (127 mg, 96%). ESI-MS calculated for C9H15N5: Exact Mass: 193.13. Found 194.14.

Workup

  1. concentrationThe product was concentrated under reduced pressure
  2. dry with materialdried under high vacuum to the title compound (i-37) (127 mg, 96%)

Sources & evidence

ORD record
ord-0295ce42d1b84493a23b3862506c7628
Source dataset
uspto-grants-2013_01
Patent number
US08354403B2

Reaction notes

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