Hydrochloric Acid → HCID 86657095, compound

HRID 1804826Notes

Reaction equation

HRID 1804826 reaction equation
[Cl-:1].[C:2]([C:5]1[CH:6]=[C:7]([CH:21]=[CH:22][C:23]=1[F:24])[CH2:8][NH+:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2F)[C:12](=[O:20])[CH:11]=[N:10]1)([OH:4])=[O:3].Cl.[Li+].[OH-:27]>>[Cl-:1].[C:2]([C:5]1[CH:6]=[C:7]([CH:21]=[CH:22][C:23]=1[F:24])[CH2:8][NH+:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][C:17]=2[OH:27])[C:12](=[O:20])[CH:11]=[N:10]1)([OH:4])=[O:3]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 86657097HCID 86657097, compound

Product 1

HCID 86657095HCID 86657095, compound

Procedure

A solution of D5 in 9% LiOH (0.05 M) was heated at 160° C. under microwaves irradiation for 15 min. The aqueous phase was made acidic with 37% HCl. The resulting precipitate was collected by filtration affording the title compound as a yellow solid.

Workup

  1. filtrationThe resulting precipitate was collected by filtration

Sources & evidence

ORD record
ord-cfe118d7175c43fa8bcd7e2e29bdd835
Source dataset
uspto-grants-2013_01
Patent number
US08354413B2

Reaction notes

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