huagongshe.com
HRID1805806

反应详情

EQUATION

反应方程式

HRID 1805806 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)[C@H](O)[C@@H](O)C(=O)O
HCID444305

L-Tartaric acid

C4H6O6

结构：CCOc1cc2c(cc1OC)C(c1cnc(N(C)C)nc1OC)=N[C@@H]1CC[C@@H](O)C[C@H]21
HCID11853488

未命名化合物

PRODUCTS

生成物

1
结构：CCOc1cc2c(cc1OC)C(c1cnc(N(C)C)nc1OC)=N[C@@H]1CC[C@@H](O)C[C@H]21.O=C(O)[C@H](O)[C@@H](O)C(=O)O
HCID11853487

未命名化合物

收率 74.4%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

2 次

结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

(2R,4aR,10bR)-6-(2-Dimethylamino-4-methoxy-pyrimidin-5-yl)-9-ethoxy-8-methoxy-1,2,3,4,4a,10b-hexahydro-phenanthridin-2-ol (42.7 mg, 0.1 mmol) are dissolved in 0.5 ml of acetone. 16.5 mg (0.11 mmol) of L-tartaric acid (dissolved in 0.5 ml of a 75:15 mixture of acetone and isopropanol) are added. The crystals are filtered off and dried to obtain 42.9 mg (74%) of the title compound (m. p.: 249° C.).

WORKUP

后处理

  1. additionare added
  2. filtrationThe crystals are filtered off
  3. customdried