Water → HCID 60108661, compound

HRID 1805890Notes

Reaction equation

HRID 1805890 reaction equation
[CH3:1][O:2][CH2:3][CH2:4]Cl.[S:6]([O-:9])([O-:8])=[O:7].[Na+:10].[Na+].O>COCCOC>[CH3:1][O:2][CH2:3][CH2:4][S:6]([O-:9])(=[O:8])=[O:7].[Na+:10]

Participants

5

Reactant 3

HCID 962WaterHCID 123162-Chloroethyl methyl etherHCID 24437Sodium Sulfite

Product 1

HCID 60108661HCID 60108661, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

To a solution of 2-chloroethyl methyl ether (Acros, 68.0 mL) in 1,2-dimethoxyethane (DME) (250 mL) was added sodium sulfite (103 g) and water (250 mL). The reaction mixture was heated at reflux for 18 hours. The solvent was removed in vacuo and the residue was extracted with methanol (500 mL). The solid was removed by filtration and washed with methanol (250 mL). The combined filtrate and washings were evaporated in vacuo to give the title compound as a white solid.

Workup

  1. temperatureThe reaction mixture was heated
  2. temperatureat reflux for 18 hours
  3. customThe solvent was removed in vacuo
  4. extractionthe residue was extracted with methanol (500 mL)
  5. customThe solid was removed by filtration
  6. washwashed with methanol (250 mL)
  7. customThe combined filtrate and washings were evaporated in vacuo

Sources & evidence

ORD record
ord-f6e9a34a61184f1493d621b7327017f8
Source dataset
uspto-grants-2013_01
Patent number
US08354539B2

Reaction notes

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