Dimethylformamide → 6-[5-(hydroxymethyl)pyrid-3-yl]-N-phenylimidazo[1,2-a]pyridine-2-carboxamide
Reaction equation
[Br:23][c:24]1[cH:25][c:26]([CH2:30][OH:31])[cH:27][n:28][cH:29]1.[CH3:109][N:110]([CH3:111])[CH:112]=[O:113].[CH3:1][Sn:2]([c:3]1[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[cH:9][c:10]([C:12](=[O:13])[NH:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[n:11]2)([CH3:21])[CH3:22].[Pd:32].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1.[c:71]1([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[cH:85][cH:86][cH:87][cH:88][cH:89]1.[c:90]1([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105][cH:106][cH:107][cH:108]1>>[c:3]1(-[c:24]2[cH:25][c:26]([CH2:30][OH:31])[cH:27][n:28][cH:29]2)[cH:4][cH:5][c:6]2[n:7]([cH:8]1)[cH:9][c:10]([C:12](=[O:13])[NH:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[n:11]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-812887cb7f9d48d99ffde072f1f1d713
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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