反应详情

HCl gas was passed through a solution of methyl 2-benzylisoindoline-5-carboxylate (56 g; 1 equiv.) in 560 ml of dichloromethane until a solid formed. The solid was filtered out, washed with hexane and dried. Methyl 2-benzylisoindoline-5-carboxylate hydrochloride (43 g) was obtained in the form of a white solid.

1. customformed
2. filtrationThe solid was filtered out
3. washwashed with hexane
4. customdried