Hydrochloric Acid → HCID 68509556, compound

HRID 1808327Notes

Reaction equation

HRID 1808327 reaction equation
[ClH:1].[CH2:2]([N:9]1[CH2:17][C:16]2[C:11](=[CH:12][CH:13]=[C:14]([C:18]([O:20][CH3:21])=[O:19])[CH:15]=2)[CH2:10]1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>ClCCl>[ClH:1].[CH2:2]([N:9]1[CH2:17][C:16]2[C:11](=[CH:12][CH:13]=[C:14]([C:18]([O:20][CH3:21])=[O:19])[CH:15]=2)[CH2:10]1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 23301778Methyl 2-benzylisoindoline-5-carboxylate

Product 1

HCID 68509556HCID 68509556, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

HCl gas was passed through a solution of methyl 2-benzylisoindoline-5-carboxylate (56 g; 1 equiv.) in 560 ml of dichloromethane until a solid formed. The solid was filtered out, washed with hexane and dried. Methyl 2-benzylisoindoline-5-carboxylate hydrochloride (43 g) was obtained in the form of a white solid.

Workup

  1. customformed
  2. filtrationThe solid was filtered out
  3. washwashed with hexane
  4. customdried

Sources & evidence

ORD record
ord-d5ed4785bd2e4d158c67517f8a6654dc
Source dataset
uspto-grants-2013_01
Patent number
US08357717B2

Reaction notes

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