Imidazole → 6-[2-(Tert-butyl-dimethyl-silanyloxy)-2-methyl-propoxy]-2-morpholin-4-yl-pyrimidin-4-ylamine
Reaction equation
[C:25]([CH3:26])([CH3:27])([CH3:28])[Si:29]([CH3:30])([CH3:31])[Cl:32].[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[NH2:1][c:2]1[cH:3][c:4]([O:14][CH2:15][C:16]([CH3:17])([OH:18])[CH3:19])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1.[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[nH:20]1[cH:21][cH:22][n:23][cH:24]1>>[NH2:1][c:2]1[cH:3][c:4]([O:14][CH2:15][C:16]([CH3:17])([O:18][Si:29]([C:25]([CH3:26])([CH3:27])[CH3:28])([CH3:30])[CH3:31])[CH3:19])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-571596512c8748d89d5ef35cc70880fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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