Dimethyl Sulfide → HCID 10473229, compound

HRID 1813920Notes

Reaction equation

HRID 1813920 reaction equation
[CH2:1]([CH:3]([O:6][C:7]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]2[C:8]=1[CH2:9][CH2:10][C:11](=O)[N:12]2[C:18]1[C:23]([CH3:24])=[CH:22][C:21]([CH3:25])=[CH:20][C:19]=1[CH3:26])[CH2:4][CH3:5])[CH3:2].CSC>C1COCC1>[CH2:1]([CH:3]([O:6][C:7]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]2[C:8]=1[CH2:9][CH2:10][CH2:11][N:12]2[C:18]1[C:23]([CH3:24])=[CH:22][C:21]([CH3:25])=[CH:20][C:19]=1[CH3:26])[CH2:4][CH3:5])[CH3:2]

Participants

4

Reactant 2

HCID 1068Dimethyl SulfideHCID 9999005HCID 9999005, compound

Product 1

HCID 10473229HCID 10473229, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared in a 86% yield as a clear oil by the method analogous to that described in Example 8 starting from 5-(1-ethyl-propoxy)-7-methyl-1-(2,4,6-trimethyl-phenyl)-3,4-dihydro-1H-[1,8]naphthyridin-2-one and BH3.DMS in THF.

Sources & evidence

ORD record
ord-addc0bcc64184af588abc2e09ed85863
Source dataset
uspto-grants-2005_04
Patent number
US06875769B2

Reaction notes

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