2-Adamantanol → 2-Adamantanol

HRID 1816087Notes

Reaction equation

HRID 1816087 reaction equation
[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[C:2]1=[O:11])[CH2:8]2.[CH:12]12[CH2:21][CH:16]3[CH2:17][CH:18]([CH2:20][CH:14]([CH2:15]3)[CH:13]1[OH:22])[CH2:19]2>>[C:1]12([OH:22])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[CH:12]12[CH2:21][CH:16]3[CH2:17][CH:18]([CH2:20][CH:14]([CH2:15]3)[C:13]1=[O:22])[CH2:19]2.[CH:1]12[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH:2]1[OH:11])[CH2:8]2

Participants

5

Reactant 2

HCID 641492-AdamantanolHCID 64151Adamantanone

Product 3

HCID 641492-AdamantanolHCID 64151AdamantanoneHCID 641521-Adamantanol

Procedure

After the completion of the reaction, the produced liquid was analyzed by means of gas chromatogram (available from Shimadzu GC-14A column, PEG=20 M, capillary column). As a result, there were obtained as the objective products, 93.8 μmol of 1-adamantanol, 22.2 μmol of 2-adamantanone and 75.7 μmol of 2-adamantanol at a yield of 19.2% with selectivity to 2-adamantanone and 2-adamantanol of 51.1%. The performance results are given in Table 1.

Workup

  1. customAfter the completion of the reaction

Sources & evidence

ORD record
ord-0ead53d28a834055b5a643f39fe63caa
Source dataset
uspto-grants-2005_04
Patent number
US06881870B2

Reaction notes

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