Hydrochloric Acid → 2',5'-Difluoro-2-((methyloxy)carbonyl)-1,1'-biphenyl-4-carboxylic acid
Reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:31][OH:32].[ClH:25].[F:1][c:2]1[c:3](-[c:9]2[c:10]([C:19](=[O:20])[O:21][CH3:22])[cH:11][c:12]([C:15](=[O:16])[O:17][CH3:18])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1.[K+:24].[OH-:23]>>[F:1][c:2]1[c:3](-[c:9]2[c:10]([C:19](=[O:20])[O:21][CH3:22])[cH:11][c:12]([C:15](=[O:16])[OH:17])[cH:13][cH:14]2)[cH:4][c:5]([F:8])[cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-0a0f15f45a5649c4bdcffccb85b649d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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