反应详情

Sodium mesoxalate monohydrate (5.00 g, 27.8 mmol) was dissolved in 1 M hydrochloric acid (50 ml) to give a colourless cloudy solution. Phenylhydrazine (3.00 g, 2.72 ml, 27.8 mmol) was added dropwise at room temperature to the stirred mixture. A yellow precipitate formed, was collected by filtration after 90 min and washed with water (50 ml). The filter cake was triturated with ethyl acetate/hexane [1:1], filtered and dried under vacuum. The title compound was isolated as a yellow powder (4.74 g, 22.7 mmol, 82%). LCMS: m/z 207 [M−H]+.

1. customto give a colourless cloudy solution
2. customA yellow precipitate formed
3. filtrationwas collected by filtration after 90 min
4. washwashed with water (50 ml)
5. customThe filter cake was triturated with ethyl acetate/hexane [1:1]
6. filtrationfiltered
7. customdried under vacuum