Potassium Carbonate → HCID 86598618, compound

HRID 1817138Notes

Reaction equation

HRID 1817138 reaction equation
[CH3:1][O:2][C:3]1[CH:61]=[C:60]([O:62][CH3:63])[CH:59]=[C:58]([O:64][CH3:65])[C:4]=1/[CH:5]=[CH:6]/[CH:7]([S:24]([CH:27](/[CH:44]=[CH:45]/[C:46]1[C:51]([O:52][CH3:53])=[CH:50][C:49]([O:54][CH3:55])=[CH:48][C:47]=1[O:56][CH3:57])[C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([NH:36][C:37](=[O:43])[CH2:38][O:39]C(=O)C)[CH:29]=1)(=[O:26])=[O:25])[C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([NH:16][C:17](=[O:23])[CH2:18][O:19]C(=O)C)[CH:9]=1.C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:57][O:56][C:47]1[CH:48]=[C:49]([O:54][CH3:55])[CH:50]=[C:51]([O:52][CH3:53])[C:46]=1/[CH:45]=[CH:44]/[CH:27]([S:24]([CH:7](/[CH:6]=[CH:5]/[C:4]1[C:3]([O:2][CH3:1])=[CH:61][C:60]([O:62][CH3:63])=[CH:59][C:58]=1[O:64][CH3:65])[C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([NH:16][C:17](=[O:23])[CH2:18][OH:19])[CH:9]=1)(=[O:25])=[O:26])[C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([NH:36][C:37](=[O:43])[CH2:38][OH:39])[CH:29]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 86598619HCID 86598619, compound

Product 1

HCID 86598618HCID 86598618, compoundYield 87.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of (E)-2,4,6-trimethoxystyryl-3-(acetoxyacetamido)-4-methoxy benzylsulfone (10 mmol) was hydrolyzed in 50% ethanol containing potassium carbonate (70 mmol) to give (E)-2,4,6-trimethoxystyryl-3-(hydroxyacetamido)-4-methoxybenzylsulfone in 87.4% yield. (m.p. 174-1 76° C.)

Sources & evidence

ORD record
ord-73096bf726054bea9e63982e5cdd0001
Source dataset
uspto-grants-2009_10
Patent number
US07598232B2

Reaction notes

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