反应详情

A mixture of N-(cyclopropylmethyl)-4-(isopropylsulfonyl)-2-nitroaniline (Step D, 521 mg, 1.8 mmol) and 10% palladium carbon (52 mg) in methanol (10 mL) and ethyl acetate (10 mL) was stirred at room temperature for 2 h under hydrogen. The mixture was filtered through a pad of celite and the filtrate was concentrated to afford the title compound (462 mg, 98%) as red brown amorphous.

1. filtrationThe mixture was filtered through a pad of celite
2. concentrationthe filtrate was concentrated