Trityl chloride → HCID 11515745, compound
Reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][OH:7].[C:8](Cl)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[C:8]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][OH:7])([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1Participants
3
Procedure
The title compound (24%) was prepared as described in example 41 but using 5-aminopentanol instead of cis-2-buten-1,4-diol in the reaction with trityl chloride.
Sources & evidence
- ORD record
- ord-118544fea4d145ad9a93c579b1f19646
- Source dataset
- uspto-grants-2009_10
- Patent number
- US07601702B2
Reaction notes
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