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HRID1821568

反应详情

EQUATION

反应方程式

HRID 1821568 的结构方程式

REACTANTS

反应物

3
结构：CN1CCOCC1
HCID7972

4-Methylmorpholine

C5H11NO

结构：CNOC.Cl
HCID81138

Methanamine, N-methoxy-, hydrochloride

C2H8ClNO

结构：CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O
HCID85083

1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-

C10H17NO4

PRODUCTS

生成物

1
结构：CON(C)C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C
HCID688298

tert-Butyl (2S)-2-[methoxy(methyl)carbamoyl]pyrrolidine-1-carboxylate

C12H22N2O4

PROCEDURE

实验过程

Boc-Proline (2.00 g, 9.29 mmol) and N,O-Dimethylhydroxylaminehydrochloride (0.91 g, 9.29 mmol) were treated as described for 1 using NMM (2 ml, 18.4 mmol) and CAIBE (1.47 ml, 9.29 mmol).