反应详情

At first, a mixture of the 4-(diallylethoxysilyl)iodobenzene (148 mg, 0.41 mmol) obtained in Example 2, tetrakistriphenylphosphine palladium (Pd(PPh3)4: 14.3 mg, 0.012 mmol), potassium carbonate (K2CO3: 85.1 mg, 0.62 mmol), and phenyl boronic acid (60 mg, 0.49 mmol) was added with distilled toluene (dist.toluene: 5 mL). Subsequently, the resultant mixture was stirred under a nitrogen atmosphere at 80° C. for 13 hours to obtain a reaction mixture. Thereafter, the reaction mixture was diluted with ether, and a salt thus formed was removed by filtering with celite. The solvent was distilled from the organic layer with an evaporator to obtain a crude product. After that, the crude product thus obtained was separated and purified by silica gel column chromatography (hexane/EtOAc=10/1), and thereby 4-(diallylethoxysilyl)biphenyl (a second organosilane compound of the present invention) was obtained (99.6 mg, 78% yield).

1. customto obtain a reaction mixture
2. customa salt thus formed
3. customwas removed
4. filtrationby filtering with celite
5. distillationThe solvent was distilled from the organic layer with an evaporator
6. customto obtain a crude product
7. customAfter that, the crude product thus obtained
8. customwas separated
9. custompurified by silica gel column chromatography (hexane/EtOAc=10/1)