Diethylamine → HCID 11610812, compound

HRID 1822169Notes

Reaction equation

HRID 1822169 reaction equation
[CH3:1][O:2][C:3]1[CH:23]=[CH:22][CH:21]=[CH:20][C:4]=1[C:5]([NH:7][S:8]([C:11]1[CH:19]=[CH:18][C:14]([C:15](Cl)=[O:16])=[CH:13][CH:12]=1)(=[O:10])=[O:9])=[O:6].[CH2:24]([NH:26][CH2:27][CH3:28])[CH3:25].C(N(CC)CC)C>C(#N)C.O>[CH2:24]([N:26]([CH2:27][CH3:28])[C:15](=[O:16])[C:14]1[CH:18]=[CH:19][C:11]([S:8]([NH:7][C:5](=[O:6])[C:4]2[CH:20]=[CH:21][CH:22]=[CH:23][C:3]=2[O:2][CH3:1])(=[O:10])=[O:9])=[CH:12][CH:13]=1)[CH3:25]

Participants

6

Reactant 3

HCID 8021DiethylamineHCID 8471TriethylamineHCID 11573931816431-72-8

Product 1

HCID 11610812HCID 11610812, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 6342AcetonitrileSolvent

Conditions

Temperature
20 °C

Procedure

To a suspension of 4-[[(2-methoxybenzoyl)amino]sulfonyl)benzoyl chloride (1 mol) and diethylamine (1 mol) in acetonitrile (1000 ml), was added triethylamine (1 mol) at 10° C. The mixture was stirred for 2 hours at 20° C. and diluted with water (500 ml). The white precipitate was filtered off, washed and dried to give the title compound. The yield of product obtained was 98% of theory, and the purity 98%.

Workup

  1. filtrationThe white precipitate was filtered off
  2. washwashed
  3. customdried

Sources & evidence

ORD record
ord-55b169c74a9540ec8847388113782010
Source dataset
uspto-grants-2009_10
Patent number
US07608736B2

Reaction notes

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