Methyl Methacrylate → Cholesterol

HRID 1823699Notes

Reaction equation

HRID 1823699 reaction equation
[SiH4].CCCCCCCCC([O:12][C@@H:13]1[CH2:26][C:25]2[C@@:16]([CH3:39])([C@@H:17]3[C@@H:22]([CH2:23][CH:24]=2)[C@@H:21]2[CH2:27][CH2:28][C@H:29]([C@@H:30]([CH2:32][CH2:33][CH2:34][CH:35]([CH3:37])[CH3:36])[CH3:31])[C@@:20]2([CH3:38])[CH2:19][CH2:18]3)[CH2:15][CH2:14]1)=O.COC(=O)C(C)=C>C(Cl)Cl>[CH3:37][CH:35]([CH2:34][CH2:33][CH2:32][C@H:30]([C@@H:29]1[C@:20]2([CH3:38])[C@H:21]([C@H:22]3[C@H:17]([CH2:18][CH2:19]2)[C@:16]2([CH3:39])[C:25]([CH2:26][C@H:13]([CH2:14][CH2:15]2)[OH:12])=[CH:24][CH2:23]3)[CH2:27][CH2:28]1)[CH3:31])[CH3:36]

Participants

5

Reactant 3

HCID 6658Methyl MethacrylateHCID 23953SilaneHCID 2723614Cholesteryl nonanoate

Product 1

HCID 5997Cholesterol

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The obtained silane copolymer 7.2 g, cholesteryl nonanoate 8 g and methylmethacrylate monomer 72 g were dissolved uniformly in 20 ml of methylene chloride under irradiation of ultrasonic wave. And then, the procedure described in Example 1 was followed, to give cholesterol liquid crystal polymer microcapsules 80 g as powders.

Sources & evidence

ORD record
ord-50ad696124f842b29d818043c01f274d
Source dataset
uspto-grants-2006_05
Patent number
US07041304B2

Reaction notes

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