反应详情

A mixture of 2,4′-dibromoacetophenone (22.4 g) and 2-amino-4-picoline (8.68 g) in ethanol (80 mL) was heated at reflux temperature for 3 hours. The reaction mixture was cooled to ambient temperature and the crystalline solid isolated by filtration, washed with ethanol and dried in vacuo to give the title compound (13.1 g).

1. temperaturewas heated
2. temperatureat reflux temperature for 3 hours
3. customthe crystalline solid isolated by filtration
4. washwashed with ethanol
5. customdried in vacuo