HCID 53794133, compound → HCID 11746630, compound

HRID 1826078Notes

Reaction equation

HRID 1826078 reaction equation
[CH2:1]([C:3](=[CH:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]>[Pd].C(OCC)(=O)C>[CH2:1]([CH:3]([CH2:9][C:10]1[CH:11]=[CH:12][C:13]([O:16][CH3:17])=[CH:14][CH:15]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH3:2]

Participants

4

Reactant 1

HCID 53794133HCID 53794133, compound

Product 1

HCID 11746630HCID 11746630, compoundYield 100.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Ethyl 2-ethyl-3-(4-methoxyphenyl)acrylate (4.58 g, 19.5 mmol), 5% palladium on carbon (500 mg) and ethyl acetate (100 mL) were mixed and hydrogenated for 8 hours at room temperature. After the catalyst was removed by filtration, the filtrate was concentrated to afford 4.63 g (100%) of the title compound as a pale yellow oil.

Workup

  1. customAfter the catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-824807bc8a6846c58bbfc67e1e4f0688
Source dataset
uspto-grants-2006_05
Patent number
US07049342B2

Reaction notes

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