Pyridine → HCID 2836987, compound

HRID 1826871Notes

Reaction equation

HRID 1826871 reaction equation
[C:1]12([C:11](Cl)=[O:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH2:14][C:15]1[CH:16]=[N:17][C:18]2[C:23]([CH:24]=1)=[CH:22][CH:21]=[CH:20][CH:19]=2.N1C=CC=CC=1>O>[N:17]1[C:18]2[C:23](=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:24]=[C:15]([NH:14][C:11]([C:1]23[CH2:10][CH:5]4[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]4)[CH2:2]2)[CH2:8]3)=[O:12])[CH:16]=1

Participants

5

Reactant 3

HCID 1049PyridineHCID 113753-AminoquinolineHCID 989151-Adamantanecarbonyl chloride

Product 1

HCID 2836987HCID 2836987, compoundYield 29%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Prepared from 1-adamantanecarbonyl chloride (0.75 g, 3.8 mmol), 3-aminoquinoline (0.60 g, 4.2 mmol), pyridine (10 mL), and water (100 mL) yielding 0.33 g (29%) of (86):

Sources & evidence

ORD record
ord-29ce079e82254b83b6eca6c4e8d45409
Source dataset
uspto-grants-2006_05
Patent number
US07053104B2

Reaction notes

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