Sodium Iodide → HCID 22048767, compound

HRID 1833036Notes

Reaction equation

HRID 1833036 reaction equation
C([O-])([O-])=O.[K+].[K+].[Na+].[I-].Cl[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[F:23])=[O:16].[CH3:24][CH:25]([CH3:41])[C:26]([NH:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([CH:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]2)[CH:30]=1)=[O:27]>>[F:23][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=1[C:15](=[O:16])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][N:38]1[CH2:39][CH2:40][CH:35]([C:31]2[CH:30]=[C:29]([NH:28][C:26](=[O:27])[CH:25]([CH3:24])[CH3:41])[CH:34]=[CH:33][CH:32]=2)[CH2:36][CH2:37]1

Participants

5

Reactant 4

HCID 5238Sodium IodideHCID 11430Potassium CarbonateHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 220492506-Chloro-1-(2-fluorophenyl)hexan-1-one

Product 1

HCID 22048767HCID 22048767, compound

Procedure

Prepared by Procedure K and Scheme E using K2CO3 instead of Na2CO3 and NaI instead of KI and 6-chloro-1-(2-fluorophenyl)-1-hexanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 439.2 (M+H)+.

Workup

  1. customPrepared by Procedure K and Scheme E

Sources & evidence

ORD record
ord-17547adbbd244f4e95b6096b449f1469
Source dataset
uspto-grants-2006_06
Patent number
US07067534B1

Reaction notes

Loading…