Triethylamine → HCID 54141893, compound

HRID 1835018Notes

Reaction equation

HRID 1835018 reaction equation
[OH:1][N:2]=[C:3]([C:12]#[N:13])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[CH:5]=1.C(N(CC)CC)C.[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[CH3:21][S:22]([O:1][N:2]=[C:3]([C:12]#[N:13])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[CH:5]=1)(=[O:24])=[O:23]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 86590799HCID 86590799, compound

Product 1

HCID 54141893HCID 54141893, compoundYield 48%

Procedure

In general analogy to the process described under 1.2, 27.7 g (0.157 mol) of α-hydroxyimino-3-methoxybenzylcyanide are reacted in the presence of 23.9 g (0.236 mol) of triethylamine with 19.8 g (0.173 mol) of methanesulfonyl chloride. Recrystallisation from toluene gives 19.1 g (48%) of α-(methylsulfonyloxyimino)-3-methoxybenzylcyanide in the form of white crystals having an m.p. of 105-107° C.

Workup

  1. customRecrystallisation from toluene

Sources & evidence

ORD record
ord-236f2c4c1bde43b483a6db3260ccc26b
Source dataset
uspto-grants-2004_08
Patent number
US06770420B2

Reaction notes

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