Acetone → HCID 9816288, compound

HRID 1835846Notes

Reaction equation

HRID 1835846 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][C:3]2([C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]2=[O:15])[CH2:2]1.[CH3:16][C:17]([CH3:19])=O.C>>[CH:17]([N:1]1[CH2:6][CH2:5][CH2:4][C:3]2([C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[NH:8][C:7]2=[O:15])[CH2:2]1)([CH3:19])[CH3:16]

Participants

4

Reactant 3

HCID 180AcetoneHCID 297MethaneHCID 9859066HCID 9859066, compound

Product 1

HCID 9816288HCID 9816288, compoundYield 75%

Procedure

The compound was prepared according to PROCEDURE 1, Method A by reaction with spiro[indoline-3,3′-piperidin]-2-one and acetone (5 equivalents). Yield: 75%. 13C NMR (CDCl3): δ 17.6, 17.7, 21.7, 32.1, 48.6, 48.8, 54.0, 54.8, 109.6, 121.6, 126.2, 127.2, 134.8, 140.1, 182.4; MS (CI, CH4): m/z (rel. int.) 245 (M+1, 100).

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-3a3ba5884ea0404f9109ac92f6373b8d
Source dataset
uspto-grants-2004_08
Patent number
US06774132B1

Reaction notes

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