Oxalic Acid → HCID 86759507, compound

HRID 1836353Notes

Reaction equation

HRID 1836353 reaction equation
[CH3:1][N-:2][C:3]1[CH:4]=[C:5]([CH:15]=[CH:16][CH:17]=1)[C:6]([CH:8]1[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]1)=[O:7].[C:18]([OH:23])(=[O:22])[C:19]([OH:21])=[O:20]>C(OCC)(=O)C>[C:18]([O-:23])(=[O:22])[C:19]([O-:21])=[O:20].[CH3:1][N-:2][C:3]1[CH:4]=[C:5]([CH:15]=[CH:16][CH:17]=1)[C:6]([CH:8]1[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH2:9]1)=[O:7]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 86759508HCID 86759508, compound

Product 1

HCID 86759507HCID 86759507, compoundYield 76.9%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4-[3-(methylamidyl)benzoyl]-1-methylpiperidine (283 mg, 1.1 mmol) in ethyl acetate was added to oxalic acid (99 mg, 1.1 mmol) in ethyl acetate. The resulting precipitate was filtered, washed with ethyl acetate, and dried under vacuum to give 270 mg (71%) of tan powder.

Workup

  1. filtrationThe resulting precipitate was filtered
  2. washwashed with ethyl acetate
  3. customdried under vacuum

Sources & evidence

ORD record
ord-2c33df228b9c46bea9b9ff598e7f534f
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

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