Hydrochloric Acid → HCID 13500733, compound

HRID 1836602Notes

Reaction equation

HRID 1836602 reaction equation
[CH2:1]([O:8][CH2:9][C@@H:10]([C:12]([OH:14])=[O:13])[NH2:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:15].[CH2:16](O)[CH3:17]>>[ClH:15].[CH2:16]([O:13][C:12](=[O:14])[C@H:10]([CH2:9][O:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[NH2:11])[CH3:17]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 78457O-benzyl-L-serine

Product 1

HCID 13500733HCID 13500733, compound

Procedure

A solution of O-benzyl-L-serine (9.75 g, 50 mmol) in ethanol (200 mL) is saturated with HCl gas for 8 minutes. The mixture is stirred overnight at room temperature, and then concentrated in vacuo. The solid is washed with diethyl ether and collected by filtration to yield O-benzyl-L-serine ethyl ester hydrochloride as a white solid.

Workup

  1. concentrationconcentrated in vacuo
  2. washThe solid is washed with diethyl ether
  3. filtrationcollected by filtration

Sources & evidence

ORD record
ord-c4999592b03443bd8f2046084df92dfc
Source dataset
uspto-grants-2004_08
Patent number
US06777443B2

Reaction notes

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