HCID 22677042, compound → HCID 22677029, compound

HRID 1837429Notes

Reaction equation

HRID 1837429 reaction equation
[CH3:1][Si:2]([CH3:18])([C:12]#[C:13][Si:14]([CH3:17])([CH3:16])[CH3:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11]>C(O)C.C(OCC)(=O)C.[OH-].[OH-].[Pd+2]>[CH3:18][Si:2]([CH3:1])([CH2:12][CH2:13][Si:14]([CH3:15])([CH3:16])[CH3:17])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11]

Participants

5

Reactant 1

HCID 22677042HCID 22677042, compound

Product 1

HCID 22677029HCID 22677029, compound

Reagents, catalysts & solvents 3

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolventHCID 8857Ethyl AcetateSolvent

Procedure

A suspension of compound 15 (15.21 g, 0.0535 mol) and palladium hydroxide on charcoal (1.85 g, 1.60 mmol) in ethanol and ethyl acetate (120 ml, 1:1) was stirred under an atmosphere of hydrogen for 24 h at room temperature. The reaction mixture was filtered (celite) and the solvent roved in vacuo to yield a clear oil.

Workup

  1. filtrationThe reaction mixture was filtered (celite)
  2. customto yield a clear oil

Sources & evidence

ORD record
ord-b8ce4e064e00406a80444d0ead25b094
Source dataset
uspto-grants-2004_08
Patent number
US06783812B2

Reaction notes

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