Hydrochloric Acid → HCID 22186112, compound

HRID 1837509Notes

Reaction equation

HRID 1837509 reaction equation
O.NN.Cl.[NH:5]1[CH2:9][CH2:8][N:7]=[C:6]1[N:10]1[CH2:19][CH2:18][C:17]2[C:12](=[CH:13][C:14]([N+:20]([O-])=O)=[CH:15][CH:16]=2)[CH2:11]1>[Ni].C(O)C>[NH:7]1[CH2:8][CH2:9][N:5]=[C:6]1[N:10]1[CH2:19][CH2:18][C:17]2[C:12](=[CH:13][C:14]([NH2:20])=[CH:15][CH:16]=2)[CH2:11]1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 24654Hydrazine hydrate (1:1)HCID 22186100HCID 22186100, compound

Product 1

HCID 22186112HCID 22186112, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

2 ml of hydrazine hydrate are added at 40° C. to a suspension of 2 g of the hydrochloride of the product obtained in Step 1 and 2 g of Raney nickel in 50 ml of ethanol. After 2 hours at 50° C., the catalyst is filtered off and the solvent is evaporated off.

Workup

  1. filtrationthe catalyst is filtered off
  2. customthe solvent is evaporated off

Sources & evidence

ORD record
ord-3cefdb3824fb4a93a3527cee873ed9ad
Source dataset
uspto-grants-2004_08
Patent number
US06784183B2

Reaction notes

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