Triethylamine → HCID 9899309, compound

HRID 1837832Notes

Reaction equation

HRID 1837832 reaction equation
[CH2:1]([N:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].[OH:8][C:9]([CH3:15])([CH3:14])[C:10]([O:12]C)=[O:11]>>[OH:8][C:9]([CH3:15])([CH3:14])[C:10]([O-:12])=[O:11].[CH2:1]([N+:3]([CH2:6][CH3:7])([CH2:4][CH3:5])[CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 8471TriethylamineHCID 75024Methyl alpha-hydroxyisobutyrate

Product 1

HCID 9899309HCID 9899309, compound

Procedure

Into a 100-mL SUS316 shaking autoclave, were charged 10 g (0.1 mol) of triethylamine and 59 g (0.5 mol) of methyl 2-hydroxyisobutyrate as a quaternizing agent, and the autoclave was shaken. After the contents of the autoclave reached 120° C., the temperature was kept there for 8 h to proceed the reaction. The reaction pressure was 0.1 MPa. After the reaction was completed, the reaction liquid was cooled and distilled to remove low-boiling components, thereby obtaining triethylmethylammonium 2-hydroxyisobutyrate at 87.4 mol % yield based on triethylamine. No decomposed product of methyl 2-hydroxyisobutyrate was detected in the gas chromatographic analysis on the distillate.

Workup

  1. stirringthe autoclave was shaken
  2. customreached 120° C.
  3. customthe reaction
  4. customThe reaction pressure
  5. customthe reaction liquid
  6. temperaturewas cooled
  7. distillationdistilled
  8. customto remove low-boiling components

Sources & evidence

ORD record
ord-c35a5edc06774c889faeab5ef1872ee6
Source dataset
uspto-grants-2004_08
Patent number
US06784317B2

Reaction notes

Loading…