Triethylamine → HCID 9899309, compound

HRID 1837834Notes

Reaction equation

HRID 1837834 reaction equation
[CH2:1]([N:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].[OH:8][C:9]([CH3:15])([CH3:14])[C:10]([O:12]C)=[O:11]>>[OH:8][C:9]([CH3:15])([CH3:14])[C:10]([O-:12])=[O:11].[CH2:1]([N+:3]([CH2:6][CH3:7])([CH2:4][CH3:5])[CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 8471TriethylamineHCID 75024Methyl alpha-hydroxyisobutyrate

Product 1

HCID 9899309HCID 9899309, compound

Procedure

Into a 5-L SUS316 autoclave equipped with an electromagnetic stirrer, were charged 505 g (5.0 mol) of triethylamine and 2950 g (25 mol) of methyl 2-hydroxyisobutyrate, and heated under stirring. After the contents of the autoclave reached 120° C., the temperature was kept there for 8 h to proceed the reaction. The reaction pressure was 0.1 MPa (Gauge). After the reaction was completed, the reaction liquid was cooled and low-boiling components were removed from the reaction liquid by distillation to obtain triethylmethylammonium 2-hydroxyisobutyrate in 87.4 mol % yield based on triethylamine.

Workup

  1. temperatureheated
  2. customreached 120° C.
  3. customthe reaction
  4. customThe reaction pressure
  5. customthe reaction liquid
  6. temperaturewas cooled
  7. customlow-boiling components were removed from the reaction liquid by distillation

Sources & evidence

ORD record
ord-5392b4a574554f95b1925756c8d44a3e
Source dataset
uspto-grants-2004_08
Patent number
US06784317B2

Reaction notes

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