反应详情

Through a solution of 10-6 (4.0 g, 16 mmol) in EtOAc (200 mL) at 0° C. was bubbled a stream of HCl gas for 10 minutes. After an additional 30 minutes, the mixture was purged with argon for 1 h and then concentrated. The residue was dissolved in acetonitrile and concentrated to give 10-7 as a yellow solid.

1. customthe mixture was purged with argon for 1 h
2. concentrationconcentrated
3. dissolutionThe residue was dissolved in acetonitrile
4. concentrationconcentrated